Current Trends in Clinical & Medical Sciences in Iris Publishers

  Ongoing COVID-19 Clinical Trials: A Pharmacological Perspective on Pneumonia Authored by Prof. Dr. Amani E Khalifa Introduction Coronavirus disease 2019; the current pandemic, is a newly emerged viral pneumonia that was named COVID-19 by the WHO on February 11th, 2020 [1]. The causative agent of this viral pneumonia is the SARS-CoV-2 which was found to be closely similar to SARS-CoV with about 80% sequence identity [2]. Although the pathogenesis of COVID-19 disease including the mechanisms of antigen presentation is poorly understood, the high similarity between SARS-CoV-2 and SARS-CoV was reflected in the clinical course of the disease where the virus typically attacks the lungs in certain vulnerable populations in three phases; viral replication, immune hyper-reactivity, and pulmonary destruction [3]. Clinical studies of COVID-19 disease The database registry of “ClinicalTrials.gov” run by the United States National Library of Medicine at the National Institutes of Health incl...

Satisfaction and Knowledge of Elderly Patients Towards Their Multiple Medications Usage Authored by SM Alqallaf Although multiple drug use or polypharmacy might be considered appropriate as in cases of concomitant diseases or in complex medical conditions, the inappropriate polypharmacy or major polypharmacy is a very common problem around the globe [1-4]. An example of that is a German study which reported the use of more than 5 medications in 26.7% of elderly patients and this doubles (54%) when including over the counter medications [1]. Nevertheless, the number of medications that constitutes polypharmacy is not fully agreed. However, WHO (2004) defined Polypharmacy as “the administration of many drugs at the same time or the administration of an excessive number of drugs “WHO 2004. Hence, polypharmacy term has been used to describe a patient’s use of multiple drugs and is used also more generally to describe unnecessary drug prescription [3,5]. The main reason for the problem o...

A Latent Growth Model Evaluation of the Comprehensive, Integrated HIV Prevention Program Effect on Excessive Alcohol Risk Awareness and Excessive Alcohol Consumption Risk Authored by Meya YB Mongkuo It has been almost four decades when HIV infection became a severe public health problem. Since then, infectious disease experts worldwide have been working without finding a vaccine to immune people from the disease. So the focus has shifted from developing a vaccine to identifying the most effective evidence-based prevention strategies to slow the spread of the disease. In 2017 an estimated 5.1 million or 14.8% of young adults aged 18 to 25 were diagnosed with substance use disorder [1,2]. Other researchers have focused on identifying evidence-based risk and protective factors and prevention strategies to slow the disease [3-8]. Research has found excessive alcohol consumption destabilize the normal functioning of virtually all vital organs that regulate behavior, including the nervous s...